Company Overview:
Jubilant Biosys is a leading biopharmaceutical company based in Bangalore, specializing in In Vitro ADME studies within our DMPK department.
Position: Research Associate I – In Vitro ADME Studies, DMPK
Organization: Jubilant Biosys
Location: Bangalore
Experience: 1 to 3 Years
Qualification: M.Pharm
Salary: ₹25,000 – ₹45,000 /month
Roles & Responsibilities:
As a Research Associate I, you will:
- Read and understand in vitro ADME protocols
- Conduct stability experiments in liver microsomes, plasma, and other matrices
- Perform in vitro ADME experiments: Experiment Type Details logP, logD, pKa measurements Analyze chemical properties CYP induction and inhibition Assess enzyme activity Permeability determinations Use Caco-2, MDCK cell lines CYP phenotyping Utilize purified enzyme systems Solubility determinations Measure in kinetic, thermodynamic, and simulated fluids
- Read and understand bioanalysis sections in study protocols
- Develop and validate LC-MS/MS and HPLC-UV/PDA methods
- Extract data from instruments and conduct bioanalytical QC
- Handle method development for various matrices (plasma, blood, tissues, urine, feces)
- Develop methods for biochemical and cell-based screening of NCEs
- Conduct biomarker estimations in multiple matrices
- Maintain and troubleshoot LC-MS/MS and HPLC instruments